2014 Autumn Conference
06 – 08 October, 2014 // Boston, MA, USA
Poster Awardees: |
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| All Poster Abstracts are available at the end of the second day |
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Day 1 (6 October 2014) |
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Concurrent Workshop Sessions |
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| Adaptive Design | R Marcus J Kando Report Back |
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| Addressing Methodological Challenges in International CNS Trials | R Keefe A Kalali Workshop  slidesReport Back |
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| Algorithms/Rules to Identify Clinical Inconsistency in the Use of Rating Scales in CNS RCTs | J Rabinowitz N Schooler Report Back |
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| Biomarkers in Schizophrenia | S Potkin D Goff Report Back |
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| Cognitive and Functional Assesssment in Clinical Trials in AD and its Precursors: Readying for Short Term and Long Term Needs | H Posner P Harvey Report Back |
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| Identifying/Reducing Effects of Non-Adherence | T Shiovitz E Bain Report Back Nonadherence: A bitter pill for drug trials (Science 17 Oct 2014, Vol 346 #6207) |
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| Implementing Innovation in CNS Clinical Trials | G Sachs M Detke Report Back |
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| Negative Symptoms | S Marder D Daniel Report Back |
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Day 2 (7 October 2014) |
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| Presidential Welcome | S Romano slides video |
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| TARGETING COGNITIVE IMPAIRMENT ACROSS CNS DISORDERS |
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| Methods, Measures and Medications – Lessons Learned from Schizophrenia |
Chairs: N Schooler I Lombardo |
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| Introduction | N Schooler* video |
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| History: What We Did Right, Unanticipated Problems and Solutions | S Marder slides video |
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| Methodology Lessons Learned and Recommendations from Positive and Negative CIAS Studies | G Haig slides video |
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| Perspective on Methodological Challenges: How Phase 2 Studies Influence Design and Conduct of Phase 3 | I Lombardo slides video |
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| Future Directions in Cognitive Impairment Associated with Schizophrenia: Social Cognition | M Green slides video |
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| Bringing Cognitive Neuroscience to Bear on Drug Development: Behavioral Tasks and Imaging Biomarkers from CNTRICS and CNTRACS for Use in Clinical Trials and Experimental Medicine Studies | C Carter slides video |
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| Panel/Audience Discussion | G Haig I Lombardo S Marder N Schooler video |
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| Report from the ISCTM Consensus Meeting on Clinical Assessment of Response to Treatment of Cognitive Impairment in Schizophrenia | R Keefe slides video |
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| Targeting Cognitive Impairment in Major Depressive Disorder | Chairs: T Laughren A Mahableshwarkar |
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| Introduction | A Mahableshwarkar slides video |
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| Cognitive Impairment in Depression: Unmet Need and Biology | A Nierenberg slides video |
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| Strategies for the Assessment of Cognitive Performance in Treatment Studies in Depression | P Harvey slides video |
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| An Industry Perspective on Targeting Cognitive Impairment in MDD | C Kurre Olsen** |
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| Regulatory Issues | K Broich slides video T Laughren slides video |
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| Panel/Audience Discussion | K Broich P Harvey T Laughren A Mahableshwarkar A Nierenberg C Kurre Olsen video |
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| Poster Session / Reception | Poster Abstracts | |
Day 3 (8 October 2014) |
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| Special Challenges: Bipolar and Epilepsy |
Chairs: G Sachs S Frangou |
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| Defining the Problem and Session Overview | G Sachs slides video |
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| Overview of the Issues for Designing Trials that Address CI Associated with Bipolar Disorder | S Frangou slides video |
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| Assessing Cognitive Function in Bipolar Disorder: Challenges and Recommendations for Clinical Trial Design | K Burdick slides video |
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| Methodological Challenges Developing Treatment for CI Associated with Epilepsy | K Meador slides video |
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| Industry Perspective Discussant: Challenges in Study Design – What Needs to be Done to Move Things Along | A Loebel slides video |
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| Panel Discussion/ Summary | K Burdick S Frangou R Goldman A Loebel K Meador G Sachs video |
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| Closing Comments/Meeting Adjourns | S Romano* video |
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| * No slides presented ** Slides and video not released
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