9-11 October 2025, Amsterdam Marriott Hotel
NI Award Submissions & Opler Prize Recommendations
22nd Annual Scientific Meeting, 18-20 February 2026, Washington DC
ISCTM DocMatter Community
Videocasts celebrating our 20th Anniversary!
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ISCTM Meeting Archives
ISCTM Meeting Archives
Videos and Presentations beginning with the 9th Annual Scientific Meeting are public access. Viewing prior materials will require logging into the ISCTM website.
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Overview of current and completed working groups, links to ISCTM guidance responses, information on joining and/or starting an ISCTM Working Group.
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Search for ISCTM related publications, access ISCTM Innovations in Clinical Neuroscience supplements.
Upcoming Calendar
9-11 October – 2025 Autumn Conference includes Joint Day with ECNP
Amsterdam Marriott Hotel, Amsterdam, The Netherlands
22 October – Lewis Alan Opler Prize Recommendations
5 November – New Investigator Award Submission Deadline
18-20 February 2026 – 22nd Annual Scientific Meeting
Washington DC
Poster Submission Deadline: 17 November
Call for Session Proposals
Session proposals are now being accepted for the 2026 Autumn Meeting or 2027 Annual Meeting.
2026 Autumn Conference Session Proposal Deadline is Noon EDT 1 October 2025.
2027 Annual Meeting Session Proposal Deadline is Noon EST 27 January 2026.
Recent Publications
ISCTM Working Group manuscripts published recently:
Innovative Technologies Working Group:
Current and emerging technologies to address the placebo response challenge in CNS clinical trials: Promise, pitfalls, and pathways forward
Orphan Disease Working Group:
Ensuring stakeholder feedback in the design and conduct of clinical trials for rare diseases: ISCTM position paper of the orphan disease working group
Algorithms and Flags Workging Group:
Consistency checks to improve measurement with the Young Mania Rating Scale (YMRS)
Innovative Technologies Working Group:
Innovative Technologies in CNS Trials: Promises and pitfalls for recruitment, retention, and representativeness
Joint ISCTM/ECNP COVID-19 CNS Clinical Trial Methodologies Blueprint Working Group:
Conducting CNS trials during a public health emergency – Lessons learned from the COVID-19 pandemic: A joint ISCTM/ECNP working group consensus paper
Assessment Methods and Endpoints for Rapid-Acting Antidepressants-RAADs Working Group:
Recommendations for Selection and Adaptation of Rating Scales for Clinical Studies of Rapid-acting Antidepressants
Estimands and Missing Data Working Group:
Defining Clinical Trial Estimands: A Practical Guide for Study Teams with Examples Based on a Psychiatric Disorder
Orphan Disease Working Group and 2020 Session Speakers:
Three Sets of Expanded Proceedings from the ISCTM Autumn Conference on Pediatric Drug Development
Negative Symptoms Working Group:
Remote Assessment of Negative Symptoms of Schizophrenia