22nd Annual Scientific Meeting Posters

Click to view poster or abstract. Posters are listed in alphabetical order by first author.

Clinician cognitive review of the Patient-Rated Substance Use Checklist (Abstract)

Alphs

Dynamic evidence integration patterns distinguish schizophrenia from healthy and psychiatric controls (Abstract)

Blanchard

Population norms of the tablet-administered Brief Assessment of Cognition (Abstract)

Brady

Speech pause and speech rate for evaluating Alzheimer’s and mild cognitive impairment: A meta-analysis (Abstract)

Cohen

Impact of cooccurring conditions on EEG biomarkers in young autistic children (Abstract)

Courtland

From clinician training to scale-specific conventions: A novel approach for LLM-based rater and data quality control (Abstract)

DeBonis

A randomized study of methods for returning APOE and pTau-217 results: eSMARTER design and recruitment (Abstract)

Erickson

Systematic review of patient focused drug development meeting reports for conditions affecting neurodevelopment (Abstract)

Farmer

Utility of patient experience data (PED) & patient preference data in patient focused drug development (PFDD) (Abstract)

Frangiosa

AI–derived subgroups from phase 2 data applied post hoc to phase 3 MDD: Could prior design adjustments have prevented failure? (Abstract)

Geraci

Frequency of rater-based efficacy assessments correlated with magnitude of placebo response in generalized anxiety disorder trials (Abstract)

Gold

Lessons learned from conducting a randomized controlled trial in patients with high risk for suicide (Abstract)

Hardy

Convergence of active and passive digital phenoptyping of changes in physical activity in younger and older adults with schizophrenia in a 52-week, open-label clinical trial of xanomeline and trospium chloride (Abstract)

Harvey

Repeated and brief assessment of real-world cognitive performance and influencing factors (Abstract)

Hernandez

Effect of consenting clinician degree on screen fail rate in Alzheimer’s disease clinical trials (Abstract)

Huoh

AI-augmented narrative screening: Using a multi-modal processing engine to reduce failure rates in central nervous system trials (Abstract)

Israel

Data patterns predict MADRS-CGI discrepancies in depression trials: Implications for rater training and data monitoring (Abstract)

Karazsia

Leveraging home video analysis with large language models to identify developmental performance insights beyond standardized assessments (Abstract)

Khan

Comparing baseline MADRS distributions by inclusionary scale use in major depression studies (Abstract)

Kott

Assessing PANSS change in screening period in acute schizophrenia clinical trials (Abstract)

Kott

Targeting angular gyrus with TMS to improve negative symptoms in schizophrenia spectrum disorders (Abstract)

Kunitoki

Integrating hybrid blinding, algorithmic pain endpoints, and exposure–response assessment in a first-in-human trial of an extended-release epidural corticosteroid (Abstract)

Lakhan

Digital twin simulation for longevity trials: A multi-domain Monte Carlo modeling framework for CNS and aging outcomes (Abstract)

Lakhan

Electrophysiological correlates of suicide risk in selective attention to mortality-related stimuli (Abstract)

Lee

Derivation and validation of a weighted composite engagement index (WCEI) to link digital therapeutic engagement with clinical outcomes in episodic migraine (Abstract)

Longenecker

Exploring the relationship between NPI-C psychosis domains and CGI-S in Alzheimer’s disease psychosis (Abstract)

Machizawa

Transdiagnostic predictors of early clinical trial dropout among youth with mental illness: A pooled secondary analysis of three adherence-promotion trials (Abstract)

McVoy

A novel speech assessment protocol for measuring emotional expression: Preliminary findings (Abstract)

Menne

Task matters: A methodological comparison of speech elicitation types for machine learning classification of psychiatric disorders and controls (Abstract)

Menne

Data quality monitoring of Bayley assessments: Error detection in rare neurodevelopmental disorder trials (Abstract)

Miller

Passive keypress and speech biomarkers for monitoring cognitive and psychosocial fluctuations in dementia caregivers (Abstract)

Moore

Memantine and exercise for cancer-related cognitive impairment during chemotherapy for breast cancer (Abstract)

Nakamura

Statistical enrichment potential using the SIGH-D in an open-label lead-in trial (Abstract)

Namaky

Standardizing audio and video capture to assess biomarkers in clinical trials – Avoiding garbage in/garbage out (Abstract)

Newton

Characterising community-based prolonged seizures and automated screening using a large language model (Abstract)

Nhu

Quantification of early treatment discontinuation: a retrospective analysis on 4,810 participants to CNS clinical trials (Abstract)

Pironet

Home-based EEG detection of REM sleep without atonia as a methodological biomarker of neurodegenerative risk (Abstract)

Sheehan

Precision imaging drug trials: Quantifying the impact of study design on fMRI biomarker sensitivity and statistical power (Abstract)

Siegel

Confirmatory factor analysis (CFA) for cognitive endpoint development: performance characteristics under misspecification, and implications for modeling and analysis (Abstract)

Simmatis

A psychometric evaluation of digital speech-based markers of negative symptom severity in schizophrenia spectrum disorders (Abstract)

Spilka

CREATE: A multimodal digital platform for emotion regulation, working memory and dopaminergic target engagement in CNS clinical trials (Abstract)

Stravoravdi

Adjusting for sex improves the screening performance of a digital cognitive assessment in an AD memory clinic cohort (Abstract)

Tröger

Impact of seltorexant on cognitive performance of adults with major depressive disorder with insomnia symptoms (Abstract)

Wegener

Effects of participation in a prospective lead-in antidepressant study on blinded MADRS scores in adjunctive antidepressant trials (Abstract)

Womack

Comparative performance of video and record-form review methods for Bayley administration fidelity (Abstract)

Wood

Investigating conversational speech latency as a digital biomarker of schizophrenia: A comparison of manual and automated approaches (Abstract)

Zhang

Machine learning generated digital twins as an external control in non-randomized trials (Abstract)

Zhuang

Choosing the appropriate rating scale for patient inclusion and primary endpoint definition in MDD trials: MADRS or HAMD? (Abstract)

zu Eulenburg