Assessment Methods and Endpoints for Rapid-Acting Antidepressants-RAADs

Chairs:  Christian Yavorsky, PhD; Jan Sedway, PhD

Most Recent Activity: Working Group Session, 20th Annual Scientific Meeting – view summary, 21-23 February 2024, Washington DC – view slides

Working Group Session, 19th Annual Scientific Meeting – view summary, 15-17 February 2023, Washington DC

Working Group Session, 18th Annual Scientific Meeting, 23-25 February 2022, Washington DC

Working Group Session, 17th Annual Scientific Meeting, 7 April 2021

 Working Group Session – 2020 Autumn Conference – 26 October 2020, View Summary. View video invitation. 

Working Group Session, 16th Annual Scientific Meeting, 21 February 2020, Washington DC – View Summary

Working Group Session, 7 September 2019, AC Bella Sky Hotel, Copenhagen, Denmark (Chairs: Elizabeth Ballard/Christian Yavorsky) View Summary
Group reviewed results of survey of clinicians assessing rapid acting ADs and followed up on items from 15th Annual meeting (see summary below).
Inaugural Working Group Session – 15th Annual Scientific Meeting-view summary – 19 February 2019, Washington DC

This working group will be focused on evaluating the validity and reliability of current and prospective future methods of assessment of efficacy, effectiveness of the “next wave” of treatments in mood disorders, utilizing the rapid acting antidepressants (RAADs) as a model. Do the instruments developed to evaluate the efficacy of older generations of treatments (e.g. MAOIs, TCAs, SSRIs) meet the needs of this new class of treatments? How well do they capture (a) speed of effect, (b) phenomenology, (c) patient experience, and (d) meaningful change?  The inaugural working group meeting will take place at the 15th Annual Scientific meeting (19-21 February 2019) with a focus on developing and refining applicable domains to help evaluate the utility of different endpoints/instruments for this new class of treatments. Strengths and weakness of standard and novel assessment methods will be compiled with the goal of holding a session to present current evidence on this topic at a future ISCTM meeting.